A No-Effect toxicity estimation package that uses brms (Bürkner (2018), https://github.com/paul-buerkner/brms) to fit concentration (dose)-response data using Bayesian methods for the purpose of estimating both Effect Concentration (ECx) values, but more particularly NEC, but more particularly 'NEC' (Fox 2010), 'NSEC' (Fisher and Fox 2023), and 'N(S)EC (Fisher et al. 2023). Please see ?bnec for more details.


Bürkner P-C (2018) Advanced Bayesian Multilevel Modeling with the R Package brms. The R Journal, 10: 395-411. doi:10.32614/RJ-2018-017.

Fisher R, Fox DR (2023). Introducing the no significant effect concentration (NSEC).Environmental Toxicology and Chemistry, 42(9), 2019–2028. doi: 10.1002/etc.5610.

Fisher R, Fox DR, Negri AP, van Dam J, Flores F, Koppel D (2023). Methods for estimating no-effect toxicity concentrations in ecotoxicology. Integrated Environmental Assessment and Management. doi:10.1002/ieam.4809.

Fox DR (2010). A Bayesian Approach for Determining the No Effect Concentration and Hazardous Concentration in Ecotoxicology. Ecotoxicology and Environmental Safety, 73(2), 123–131. doi: 10.1016/j.ecoenv.2009.09.012.